Advances in Self-Emulsifying Drug Delivery Systems: Supersaturated, Solid, Hybrid, 3D Printed and Computationally Optimized Approaches

Recent developments, including supersaturation SED Interprovincial Developmental Special Education Council (Su-SEDDS), solid SEDS (S-SEDDS), hybrid systems, 3D printing technologies, and computational modelling, have greatly improved their performance. Su-SEDDS enhance the rate of drug absorption by exerting supersaturation, and S-SEDDS improve stability and patient compliance. Hybrid systems and 3D Printing for targeted and Personalized Drug Delivery. Computational modelling is further used to optimise formulation design and to help predict in vivo behaviour. In the present review, all these innovations and their impact on today's drug delivery are fully discussed.