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Journal of Pharmaceutical Research and Integrated Medical Sciences

Vaishali Bhagwani Bhagwani

Author Profile
K.P. Singh Memorial Institute of Pharmacy, Sitapur, U.P, India. 261207
1
Publications
1
Years Active
6
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51
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Publications by Vaishali Bhagwani Bhagwani

1 publication found • Active 2026-2026

2026

1 publication

AI-Accelerated Discovery of Novel Gero-suppressive Compounds: Quantifying the Enhancement of the Human Health span-To-Lifespan Ratio

with Yash Srivastav Srivastav, Stuti Verma Verma, Kamini Prajapati Prajapati, Vasu Tiwari Tiwari, Neha Rawat Rawat, Shivani Singh Singh
2026

This current study focuses on the impact of Artificial Intelligence (AI) on the rapid identification of new molecules to suppress aging processes, which increases the proportion of healthspan relative to lifespan. The research approach taken involved a quantitative method, where artificial intelligence-based machine learning, bioinformatics, and statistical analysis were used alongside computational molecular docking. Biochemical information from databases such as PubChem, DrugBank, and ChEMBL was leveraged to screen and analyze molecular data. It was observed that AI-assisted predictive models, especially Deep Learning Neural Networks, offered highly accurate predictions concerning the biological activity of anti-aging compounds. The selected molecules showed considerable decreases in oxidative stress, inflammation, and cellular senescence markers, coupled with improved mitochondrial function and cell repair. Moreover, quantitative results showed that the use of AI for predicting the efficacy of anti-aging agents led to more significant healthspan enhancements than lifespan increases.