Saurabh Shrivastava

This study examines the impact of hypertension and diabetes on patients in the local areas of Durg City, Chhattisgarh. A cross-sectional survey was conducted among patients in Durg City diagnosed with hypertension, diabetes, or both, across different age groups and socioeconomic backgrounds. Data were collected through interviews, medical records, and health check-ups at local clinics. The study assessed prevalence, awareness, treatment patterns, lifestyle factors, and complications. Results showed a high incidence of both conditions, often coexisting, with poor awareness and disease management in certain groups. Unhealthy diets, physical inactivity, and stress were major contributing factors. The study highlights the need for stronger public health efforts, awareness programs, and accessible healthcare services. It provides a foundation for future research and local health policies to improve prevention and management of these chronic diseases.

Vesicular drug delivery systems have revolutionized pharmaceutical technology by enhancing therapeutic efficacy, improving drug stability, and enabling targeted and controlled release. Among them, lipoidal and non-lipoidal vesicles represent two distinct yet complementary approaches in nanocarrier design. Lipoidal vesicles, such as liposomes, ethosomes, and transfersomes, are primarily composed of phospholipids and mimic biological membranes, offering excellent biocompatibility and encapsulation of lipophilic drugs. In contrast, non-lipoidal vesicular systems, including polymersomes, dendrimers, and other polymer-based carriers, utilize synthetic or natural polymers to achieve greater structural stability, tunable release profiles, and enhanced physicochemical versatility. 

Botanical antioxidants like flavonoids and polyphenols offer promising  natural UV protection but suffer from low SPF (