Infectious leucorrhoea is one of the most prevalent diseases of gynecologic nature involving infection of the reproductive system by fungi, bacteria, and parasites. Recurrent vaginal infections may lead to microbial cross-infections between male sex partners, adversely affecting sexual relations and intimate connections in the couple. This paper attempted to examine the problem of cross-infection, the state of urogenital health of men involved in the research, and the effect of infectious leucorrhoea on sexual arousal in both parties. A cross-sectional observational clinical study was carried out among 80 couples undergoing gynecology and urology clinics visits due to complaints of infectious vaginal discharge. Clinical evaluation, microbial investigation, laboratory tests, and questionnaire were used in the process of information collection. The results have shown that C. albicans was the most common pathogen among women in the sample group. Dysuria, balanitis, and penile irritation were found among men involved in the research, suggesting possible cross-infection from women. Sexual desire loss and avoidance behavior were noticed as well. Analysis of statistics indicates that there were highly significant relationships between infections with leucorrhoea, urogenital problems among men, and compromised sexual wellbeing (p